张黎明

个人基本简介: 

博士,教授

材料化学与物理专业博士生导师

高分子化学与物理专业博士生导师

生物医学工程专业博士生导师

联系电话:+86-20-84112354 (O)

电子邮箱:ceszhlm@mail.sysu.edu.cn

个人网站:http://zhangliming.polymer.cn/

主要经历: 

1994年进入中山大学高分子研究所做博士后研究, 两年后留校任教至今。先后任副教授(1996)、教授(2002)、博士生导师(2003),兼任中山大学高分子研究所教研室主任(1997)、副所长(1998)、教工党支部书记(1999)、所长(2013)、新型聚合物材料设计合成与应用广东省普通高校重点实验室主任(2013);2001-2002年,在美国纽约州立大学Stony Brook分校化学系任Research Specialist;2011-2012年,在美国斯坦福大学化学系任Visiting Fellow。近10余年来,作为课题负责人已主持包括7项国家自然科学基金面上项目在内的国家和省部级科研项目20多项,并参与国家973重大项目(主要学术骨干)、863计划项目(合作单位负责)等多项课题研究,还先后与东莞泰合复合材料有限公司(台资)、广东恒业精细化工有限公司、中山大学附属医院和基础医学院、广州军区总医院、南方医科大学南方医院和珠江医院、广东博迪思迈医疗器械有限公司、广州市纤维产品检测院等单位开展科研合作。已负责指导博士后6人、访问学者1人、博士生21人、硕士生30人,还参与承担两项国家自然科学基金委基础科学人才培养基金能力提高项目,指导的10多名本科生先后获得国家大学生创新训练计划项目资助,2012年被聘为中山大学逸仙学院拔尖学生实验班导师。

学科方向: 

1. 医用高分子与纳米生物技术
2. 天然大分子改性及其功能化
3. 聚电解质及其凝胶与复合物
4. 纳米杂化材料与高性能树脂
5. 涂料和油墨及高分子型助剂

荣誉获奖: 

1999 入选教育部高等学校骨干教师资助计划

2000 中山大学优秀共产党员

2000 中山大学马应彪奖教奖

2000 广东省高等学校“千百十工程”校级培养对象

2003 广东省科学技术奖(自然科学类)三等奖(排名第一)

2004 入选教育部新世纪优秀人才支持计划

2005 中山大学优秀共产党员

2007 中山大学化学与化学工程学院芙兰励教奖

2007 广东省科学技术奖(自然科学类)二等奖(排名第一)

2008 广东省高等学校“千百十工程”省级培养对象

2010 广东省科学技术奖(自然科学类)二等奖(排名第一)

2013 广东省科学技术奖(自然科学类)二等奖(排名第一)

2014 中山大学化学与化学工程学院服务奖

2014 中山大学化学与化学工程学院美乐仕奖教奖

主要兼职: 

兼任《高分子通报》、《纤维素科学与技术》、《石油学报(石油加工)》、《腐植酸》、《中国组织工程研究与临床康复》、《Frontiers in Chemistry》、《Frontiers in Materials》、《Advanced Chemical Engineering Research》、《Molecules & Medicinal Chemistry》等学术杂志编委,现为全国材料新技术发展研究会常务理事、广东省石油学会常务理事、广东省人体生物组织工程学会理事、广东省材料研究学会理事、广东省生物医学工程学会生物材料专业委员会委员、广东省化学学会高分子化学专业委员会委员、全国质量监管重点产品检验方法标准化技术委员会委员。

代表论著: 

2012
1.(with Lin, J. T.; Li, C. H.; Zhao, Y.; Hu, J. C. ) Co-electrospun Nanofibrous Membranes of Collagen and Zein for Wound Healing. ACS Applied Materials and Interfaces, 2012, 4(2): 1050-1057.
2.(with Ma, D.; Zhang, H. B.; Tu, K.) Novel supramolecular hydrogel / micelle composite for co-delivery of anticancer drug and growth factor. Soft Matter, 2012, 8(13): 3665-3672.
3.(with Ma, D.; Lin, J.; Chen, Y.; Xue, W.) In-situ gelation and sustained release of an antitumor drug by graphene oxide nanosheets. Carbon, 2012, 50: 3001-3007.
4(with Zhou, Y.; Yang, B.; Ren, X.; Liu, Z.; Deng, Z.; Deng, Y.; Yang, L.) Hyperbranched cationic amylopectin derivatives for gene delivery. Biomaterials, 2012, 33: 4731-4740.
5.(with Lao, G.; Yan, L.; Yang, C.; Zhang, S.; Zhou, Y.) Controlled release of epidermal growth factor from hydrogels accelerates wound healing in diabetic rats. Journal of the American Podiatric Medical Association, 2012, 102(2): 89-98.
6.(with Zhou, H.; Yang, L.; Cheng, L.; Zheng, H.; Lan, Y.) Down-regulation of VEGF mRNA expression by triamcinolone acetonide acetate-loaded chitosan derivative nanoparticles in human retinal pigment epithelial cells. International Journal of Nanomedicine, 2012, 7: 4649-4660.

2011

7.(with Ma D.) Supramolecular Gelation of a Polymeric Prodrug for Its Encapsulation and Sustained Release. Biomacromolecules, 2011, 12(9): 3124-3130. 
8.(with Deng, J.; Luo, Y.) PEGylated polyamidoamine dendron-assisted encapsulation of plasmid DNA into in-situ forming supramolecular hydrogel for sustained gene delivery. Soft Matter, 2011, 7: 5944-5947.
9.(with Ma, D.; Zhang, H. B.; Chen, D. H) Novel supramolecular gelation route to in-situ entrapment and sustained delivery of plasmid DNA. Journal of Colloid and Interface Science, 2011, 364: 566-573.
10.(with Deng, J.; Li, N.; Mai, K.; Yang, C.; Yan, L.) Star-shaped polymers consisting of a
ß-cyclodextrin core and poly(amidoamine) dendron arms: Binding and release studies with methotrexate and siRNA. Journal of Materials Chemistry, 2011, 21(14): 5273-5281.
11.王红飞,杨浩,张黎明. 具酯酶活性的温敏型分子印迹微凝胶. 中国科学: 化学, 2011, 41(3): 524-530.
12.(with Deng, J.; Zhou, Y.; Xu, B.; Mai, K.; Deng, Y.) Dendronized chitosan derivative as a biocompatible gene delivery carrier. Biomacromolecules, 2011, 12(3): 642-649.
13.(with Wang, G. H.; Xing, Z.) Polysaccharide-assisted incorporation of multiwalled carbon nanotubes into sol-gel silica matrix for electrochemical sensing. Journal of Materials Chemistry, 2011, 21(12): 4650-4656.
14.(with He, F. -A.; Fan, J. -T.; Song, F.; Lai-Wa, C.-H.) Fabrication of hybrids based on graphene and metal nanoparticles by in situ and self-assembled methods. Nanoscale, 2011, 3: 1182-1188.
15.(with Wang, H.-F.; Yang, H.) Temperature-sensitive molecularly imprinted microgels with esterase activity. Science China: Chemistry, 2011, 54(3): 515-520.
16.(with Lu, H.-W.; Wang C.; Chen R.-F.) Preparation and properties of new micellar drug carriers based on hydrophobically modified amylopectin. Carbohydrate Polymers, 2011, 83: 1499-1506.
17.(with Ma, D.; Xie, X.; Liu, T.; Xie, M. Q.) Tunable Supramolecular Hydrogel for in-situ Encapsulation and Sustained Release of Bioactive Lysozyme. Journal of Colloid and Interface Science, 2011, 359: 399-406.
18.(with Nie, L.; Wu, Z.) Magnetic/polymer/nanogold complex using as a novel enzyme support. Journal of Nanoscience and Nanotechnology, 2011, 11: 5223-5227.
19.(with Yang, L.; Yang, B.; Zeng, D.; Wang, D.; Wang, Y.) Formation and property of a novel complex composed of amylose-grafted chitosan derivative and single-walled carbon nanotubes. Carbohydrate Polymers, 2011, 85: 845-853.
 

2010
20.(with Ma, D.; Tu, K.) Bioactive supramolecular hydrogel with controlled dual drug release characteristics. Biomacromolecules, 2010, 11(9): 2204-2212.
21.(with Hu, R.; Chen, Y.-Y.) Synthesis and characterization of in-situ photogelable polysaccharide derivative for drug delivery. International Journal of Pharmaceutics, 2010, 393: 96-103.
22.(with Song, F.; Shi, J.-F.; Li, N.-N.) Viscoelastic and fractal characteristics of a supramolecular hydrogel hybridized with clay nanoparticles. Colloids and Surfaces B: Biointerfaces, 2010, 81: 486-491.
23.(with Yang, L.; Fu, S.; Zhu, X.; Yang, Y.; Yang, X.; Liu, H.) Hyperbranched acidic polysaccharide from green tea. Biomacromolecules, 2010, 11(12): 3395 - 3405.
24.(with Song, F.; Shi, J.-F.; Li, N.-N.) Novel casein hydrogels: Formation, structure and controlled drug release. Colloids and Surfaces B: Biointerfaces, 2010, 79: 142-148.
25.(with Li, H.-P.; Ma, B.-G.; Zhou, S.-M.; Yi, J.-Z.) Thermally responsive graft copolymer of soy protein isolate and N-isopropylacrylamide: Synthesis and self-assembly behavior in aqueous solution.Colloid and Polymer Science, 2010, 288: 1419-1426.
26.(with He, F.; Fan, J.; Ma, D.; Leung, C.; Chan, H.-L.) The attachment of Fe3O4 nanoparticles to graphene oxide by covalent bonding. Carbon, 2010, 48 (11): 3139-3144.
27.(with Song, F.; Shi, J.-F.; Li, N.-N.; Yang, C.; Yan, L.) Using hydrophilic polysaccharide to modify supramolecular hydrogel from a low-molecular-mass gelator. Materials Science and Engineering C: Materials for Biological Applications, 2010, 30: 804-811.
28.(with Cai, X.; Yang, L.; Wu, Q.) Valuation of amylose used as a drug delivery carrier. Carbohydrate Research, 2010, 345: 922-928.
29.(with Chen, J.; Yi, J.-Z.) Water in dextran hydrogels. Journal of Applied Polymer Science,2010, 117: 1631-1637.
30.(with Wang, X.; Wang, G. -H.; Zhang, J.-X.) Viscoelastic measurement of complex fluids using forced-oscillating torsion resonator with continuously-varying-frequency capability. Rheologica Acta, 2010, 49(11-12): 1117-1126.
31.(with Chen, L.-Q.; Chen, J.-J.; Yang, J.; Li, R.-X.) Self-assembly and drug delivery behaviors of a novel thermo-sensitive block glycopolymer. Chinese Science Bulletin, 2010, 55 (36): 4187-4196.
32.(with Chen, L.-Q.; Chen, J.-J.; Yang, J.; Li, R.-X.) Synthesis and self-assembly behavior of a novel amphiphilic block glycopolymer. Chemical Journal of Chinese Universities, 2010, 31(8): 1676-1681.
33.(with Li, B.-G.) Reseach progress in inclusion complexation of amylose. Progress in Chemistry, 2010, 22(6): 1161-1168.
34.(with Wang, H.-F.; Tang, C.-Y.; Yang, H.) Study on enzyme mimics of molecularly imprinted microgels.Chemical Journal of Chinese Universities, 2010, 31(12): 2488-2493.
35.(with Wang, H. -F.) Molecularly Imprinted Functional Materials Based on Polysaccharides. Progress in Chemistry, 2010, 22(11): 2165-2172.
36.(with Yang, L.; Lan, Y. -Q.; Guo, H.; Cheng, L. -Z.; Fan, J. -Z.; Cai, X.; Chen, R. -F.; Zhou, H. -S.) Ophthalmic drug-loaded carboxymethyl chitosan hydrogels: Synthesis, in vitro and in vivo evaluation.Acta Pharmacologica Sinica, 2010, 31(12): 1625-1634.
 

2009
37.(with Wang, G. -H.) A biofriendly silica gel for in-situ protein entrapment: Biopolymer-assisited formation and its kinetic mechanism. The Journal of Physical Chemistry B, 2009, 113(9): 2688-2694.
38.(with Song, F.; Li, N.-N.; Shi, J.-F.) In-situ crosslinkable hydrogel formed from a polysaccharide-based hydrogelator. Biomacromolecules, 2009, 10(4): 959-965.
39.(with Ma, D.; Xie, X.) A novel route to in-situ incorporation of silver nanoparticles into supramolecular hydrogel networks. Journal of Polymer Science Part B: Polymer Physics, 2009, 47: 740-749.
40.(with Song, F.) Gelation modification of soy protein isolate by a naturally occurring crosslinking agent and its potential biomedical application. Industrial & Engineering Chemistry Research, 2009, 48(15): 7077-7083.
41.(with Song, F.; Yang, C.; Yan, L.) Genipin-crosslinked casein hydrogels for controlled drug delivery.International Journal of Pharmaceutics, 2009, 373: 41-47.
42.(with Ma,Y.-Q; Yi, J.-Z.) A facile approach to incorporate silver nanoparticles into dextran-based hydrogels for antibacterial and catalytical applications. Journal of Macromolecular Science Part A: Pure and Applied Chemistry, 2009, 46(6): 643-648.
43.(with Yang, L.-Q.) Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources. Carbohydrate Polymers, 2009, 76: 349-361.
44.(with Wang, L.) Viscoelastic characterization of a new guar gum derivative containing anionic carboxymethyl and cationic 2-hydroxy-3- (trimethylammonio) propyl substituents. Industrial Crops and Products, 2009, 29: 524-529.
45.(with Cai, X.; Yang, L.-Q.; Wu, Q.) Synthesis and anaerobic biodegradation of indomethacin conjugated cellulose ethers used for colonic targeted drug delivery. Bioresource Technology, 2009, 100: 4164-4170.
46.(with Ma, D.) Fabrication and modulation of magnetically supramolecular hydrogels. The Journal of Physical Chemistry B, 2008, 112(20): 6315-6321.
 

2008
47.(with Song, F.) Enzyme-catalyzed formation and structure characteristics of a protein-based hydrogel.The Journal of Physical Chemistry B, 2008, 112: 13749-13755.
48.(with Lu, H.-W.; Liu, J.-Y.; Chen, R.-F.) Synthesis of an amphiphilic polysaccharide derivative and its micellization for drug release. Journal of Bioactive and Compatible Polymers, 2008, 23: 154-170.
49.(with Li, B.-G.) Synthesis and characterization of novel amphiphilic block copolymers based on maltoheptaose and poly(ε-caprolactone). Carbohydrate Polymers, 2008, 74: 390-395.
50.(with Ma, D.) UV photopolymerized hydrogels with β-cyclodextrin moieties. Journal of Polymer Research, 2008, 15(4): 301-307.
51.(with Yi, J.-Z.) Removal of methylene blue dye from aqueous solution by adsorption onto sodium humate/polyacrylamide/clay hybrid Hydrogels. Bioresource Technology, 2008, 99: 2182-2186.
52.(with Yi, J.-Z.; Ma, Y.-Q.) Synthesis and decoloring properties of sodium humate / poly(isopropylacrylamide) hydrogels. Bioresource Technology, 2008, 99(13): 5362- 5367.
53.(with Yang, L.; Kuang, J.; Wang, J.) Loading and in vitro controlled release of indomethacin in polymeric micelles prepared from amphiphilic cholesteryl-bearing carboxymethylcellulose derivatives.Macromolecular Bioscience, 2008, 8(3): 279-286.
54.(with Yang,L.; Zhang, B.; Liang, Y.; Yang, B.; Kong, T.) In situ synthesis of amylose/single-walled carbon nanotubes supermolecular assembly. Carbohydrate Research, 2008, 343(14): 2463-2467.
55.(with Yang, L.; Kuang, J.; Li, Z.; Zhang, B.; Cai, X.) Amphiphilic cholesteryl-bearing carboxymethylcellulose derivatives: self-assembly and rheological behaviour in aqueous solution.Cellulose, 2008, 15(5): 659-669.
 

2007
56.(with Liang, Y.-Y.) Bioconjugation of papain on superparamagnetic nanoparticles decorated with carboxymethylated chitosan. Biomacromolecules, 2007, 8(5): 1480-1486.
57.(with Wang, G. -H.) Manipulating formation and drug- release behavior of new sol-gel silica matrix by hydroxypropyl guar gum. The Journal of Physical Chemistry B, 2007, 111(36): 10665-10670.
58.(with Liang, Y.-Y.; Jiang, W.; Li, W.) Embedding magnetic nanoparticles into responsive polysaccharide-based hydrogels for magnetically assisted bioseparation. ChemPhysChem, 2007, 8: 2367- 2372.
59.(with Yi, J.-Z.) Studies of sodium humate / polyacrylamide/ clay hybrid hydrogels. I. Swelling and rheological properties of hydrogels. European Polymer Journal, 2007, 43: 3215-3221.
60.(with He, F. A.; Jiang, H.-L.; Wu, Q.; Wang, H.-H.) A new strategy to prepare polyethylene nanocomposites by using a late-transition-metal catalyst supported on AlEt3-activated organoclay.Composites Science and Technology, 2007, 67: 1727-1733.
61.(with Yi, J.-Z.) Study on hybrid hydrogels based on humic acid, polyacrylamide and clay. Acta Polymerica Sinica, 2007, (5): 502-505.
62.(with He, F. A.) New Polyethylene nanocomposites prepared by in-situ polymerization method using nickel a-diimine catalyst supported on organo-modified ZnAl layered double hydroxide. Composites Science and Technology, 2007, 67: 3226-3232.
63.(with He, F. A.) Organo-modified ZnAl layered double hydroxide as new catalyst support for the ethylene polymerization. Journal of Colloid and Interface Science, 2007, 315: 439-444.
64.(with Shi, H.-Y.) New grafted polysaccharides based on O-carboxymethyl-O-hydroxypropyl guar gum and N-isopropyl- acrylamide: Synthesis and phase transition behavior in aqueous media. Carbohydrate Polymers, 2007, 67: 337–342.
65.(with Yang, L.; Zhang, B.-F.; Wen, L.; Liang, Q.) Amphiphilic cholesteryl grafted sodium alginate derivative: Synthesis and self-assembly in aqueous solution. Carbohydrate Polymers, 2007, 68(2): 218-225.
66.(with Liu, J.-Y.) Preparation of a polysaccharide–polyester diblock copolymer and its micellar characteristics. Carbohydrate Polymers, 2007, 69: 196-201.
67.(with Wang, G. -H.) Reinforcement in thermal and viscoelastic properties of polystyrene by in-situ incorporation of organophilic montmorillonite. Applied Clay Science, 2007, 38: 17-22.
68.(with Liang, Y.-Y.; Li, W.; Chen, R.-F.) Polysaccharide- modified iron oxide nanoparticles as effective magnetic affinity adsorbent for bovine serum albumin. Colloid and Polymer Science, 2007, 285(11): 1193-1199.
69.(with Kong, T.; Hui, P.) Semi-dilute solutions of hydroxypropyl guar gum: Viscosity behaviour and thixotropic properties. Journal of the Science of Food and Agriculture, 2007, 87: 684–688.
70.(with Yi, J.-Z.) Biodegradable Blend Films Based on Two Polysaccharide Derivatives and Their Use as Ibuprofen-Releasing Matrices. Journal of Applied Polymer Science, 2007, 103: 3553–3559.
71.(with Li, J.-M.) Characteristics of novel starch-based hydrogels prepared by UV photopolymerization of acryloylated starch and a zwitterionic monomer. Starch-Starke, 2007, 59: 418-422.
72.(with He, F. A.; Jiang, H.-L.; Wu, Q.; Wang, H. -H.) Polyethylene nanocomposites obtained from in-situ polymerization using supported Ziegler-Natta catalyst system. Journal of Macromolecular Science Part A: Pure and Applied Chemistry, 2007, 44: 11–15.
73.(with Shi, H.-Y.; Ma, Y.-Q.; Yi, J. -Z.) Synthesis and characterization of water-soluble cellulose derivatives with thermo- and pH-sensitive functional groups. Journal of Macromolecular Science Part A: Pure and Applied Chemistry, 2007, A44(10): 1109-1113.
74.(with Liu, J.-Y.) Metal-free initiator /catalyst systems for the ring opening polymerization of cyclic ester monomers. Progress in Chemistry, 2007, 19(2): 350-355.
 

2006
75.(with Zhao, S.-P.; Ma, D.; Yang, C.; Yan, L.) Fabrication of novel supramolecular hydrogels with high mechanical strength and adjustable thermosensitivity. The Journal of Physical Chemistry B, 2006, 110(33): 16503-16507.
76.(with Wang, G. -H.) Using novel polysaccharide-silica hybrid material to construct amperometric biosensor for hydrogen peroxide. The Journal of Physical Chemistry B, 2006, 110(49): 24864-24868.
77.(with Zhao, S.-P.; Ma, D.) Supramolecular hydrogels induced rapidly by inclusion complexation of poly(ε-caprolactone)- poly(ethylene glycol)-poly(ε-caprolactone) block copolymers with α-cyclodextrin in aqueous solutions. The Journal of Physical Chemistry B, 2006, 110(25): 12225-12229.
78.(with He, F. A.) Using inorganic POSS-modified Laponite clay to support nickel α-diimine catalyst for in-situ formation of high performance polyethylene nanocomposites. Nanotechnology, 2006, 17: 5941-5946.
79.(with Zhao, S.-P.; Ma, D.) New semi-interpenetrating network hydrogels: Synthesis, characterization and properties. Macromolecular Bioscience, 2006, 6: 445-451.
80.(with Zhou, Y. –J.; Wang, Y.) Novel hybrid hydrogel incorporated hydrophilic clay for the efficient removal of water-soluble cationic dye. Journal of Chemical Technology and Biotechnology, 2006, 81(5): 799-804.
81.(with Zhou, J.-F.) Synergistic viscosity characteristics of aqueous mixed solutions of hydroxypropyl- and carboxymethyl hydroxypropyl- substituted guar gums. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2006,279: 34-39.
82.(with Kong, T.) Aqueous polysaccharide blends based on hydroxypropyl guar gum and carboxymethyl cellulose: synergistic viscosity and thixotropic properties. Colloid and Polymer Science, 2006, 285(2): 145-151.
83.(with Wang, G. H.; Chen, X. -D.; Zhu, F.-M.; Wu, Q.) The synthesis of novel hybrid polymers containing polyhedral oligomeric silsesquioxane. Progress in Chemistry, 2006, 18(4): 453-458.
84.(with He, F. –A.; Yang, F.; Chen, L.–S.; Wu, Q.) New nanocomposites based on syndiotactic polystyrene and organo-modified ZnAl layered double hydroxide. Journal of Polymer Research, 2006, 13(6): 483-493.
85.(with Shi, H.-Y.) Phase transition and aggregation characteristics of a thermoresponsive dextran derivative in aqueous solutions. Carbohydrate Research, 2006, 341(14): 2414-2419.

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