陈永明

个人基本简介: 

职位:博士,教授,博士生导师,高分子化学与物理专业。

中科院“百人计划”获得者(2000年,终期考核优秀)。

国家杰出青年科学基金获得者(2006年)。

联系方式

邮箱:chenym35@mail.sysu.edu.cn
通讯地址:广东省广州市中山大学化学与化学工程学院
邮编:510275
个人网站:http://biomaterials.sysu.edu.cn/chenlab/

主要经历: 

1984.4-1987.8 西安七十中学,教学; 

1994.3-1996.4 中国科学院化学研究所,博士后研究,导师习复研究员;

1996.6-1998.9 中国科学院化学研究所,副研究员;

1998.10-2000.6 德国杜塞尔多夫大学,博士后研究,G. Wulff教授组;

2000.7-2001.8 德国美因茨大学博士后研究,M. Schmidt教授组;

2001.9-2013.10 中国科学院化学研究所,研究员;

2013.10 至今 中山大学化学与化学工程学院。中山大学“百人计划”引进人才。

中国化学会高分子学科委员会成员(2011年起); Polymer期刊(Elsevier出版物)副主编(2007年起); Polymer期刊(Elsevier出版物)顾问委员会(Editorial Advisory Board,2006-2007年); Macromolecules期刊(ACS出版物)顾问委员会(Editorial Advisory Board,2010年起); ACS Macro Letters期刊(ACS出版物)顾问委员会(Editorial Advisory Board,2011年起); Chinese Journal of Polymer Science期刊(中国化学会)编委(2012年起); 《离子交换与反应性高分子》期刊编委(2008年起)。

学科方向: 

高分子合成化学,链结构精密控制方法,聚合物的自组装及纳米材料,新型功能高分子材料。

荣誉获奖: 

中国化学会高分子基础研究王葆仁奖(2011年)

1、拓扑高分子的合成方法:研究聚合物一级链结构和拓扑结构的合成方法学,建立了具有一定普适性的简便合成星形聚合物方法,发展了制备大分子单体和类树状聚合物的新方法,提出可逐级降解、可进行拓扑链转变的星形聚合物。

2、蠕虫形聚合物的精密合成:建立了树状化聚合物和聚合物分子刷的多种合成方法学,可简便、高效、较大量合成蠕虫形纳米单分子,实现其尺寸(从几十至几百纳米)、结构和组成的控制。

3、嵌段聚合物控制纳米颗粒结构和几何形状:通过嵌段共聚物的溶液和本体自组装及选择区域交联,研究原位制备有机/无机杂化纳米粒子的方法。制备了球形、囊泡、复合囊泡等多种结构固定的纳米粒子,首次观察到内部高度折叠双分子膜的嵌段共聚物复杂囊泡,建立了可较大量制备球形、柱形、片形等形状聚合物纳米颗粒的简便普适方法。

4、新型聚合物功能材料:从分子链结构的可控发展聚合物新材料。由环糊精和聚合物的超分子作用制备了响应性、可注射、杂化碳纳米管的各种超分子水凝胶,开发其在药物输送方面的应用;提出一种简单多功能聚合物纳米药物载体体系;提出一种通过动态共价键在温和条件下对软材料进行原位自愈合的新机理。 发表SCI论文130余篇,在Macromol. Rapid Comm.和Chem. Comm.分别发表Feature Article各1篇,在Macromolecules发表Perspective Article 1篇,在《高分子学报》发表专论1篇。

主要兼职: 

国家自然科学基金会重大项目1项(拓扑高分子的精密合成,2011-2015,项目负责人)。

国家自然科学基金会杰出青年科学基金(2007-2010,项目负责人)。

国家自然科学基金会重点项目1项(2006-2009,项目骨干)。

国家自然科学基金会面上项目4项(1997-2012,项目负责人)。

代表论著: 

Du, J. Z.; Chen, Y. M.; Zhang, Y. H.; Han, C. C.; Fischer, K.; Schmidt, M. "Organic/inorganic hybrid vesicles based on a reactive block copolymer", J. Am. Chem. Soc. 2003, 125(48), 14710-14711.

Deng, G. H.; Chen, Y. M. "A novel way to synthesize star polymers in one pot by ATRP of N-[2-(2-bromoisobutyryloxy)ethyl]maleimide and styrene", Macromolecules 2004, 37(1), 18-26.

Du, J. Z.; Chen, Y. M. "Star polymer, PCL-PS heteroarm star polymer by ATRP, and core-carboxylated PS star polymer thereof", Macromolecules 2004, 37(10), 3588-3594.

Du, J. Z.; Chen, Y. M. "Preparation of organic/inorganic hybrid hollow particles based on gelation of polymer vesicles", Macromolecules 2004, 37(15), 5710-5716.

Du, J. Z.; Chen, Y. M. "Atom-transfer radical polymerization of a reactive monomer: 3-(Trimethoxysilyl)propyl methacrylate", Macromolecules 2004, 37(17), 6322-6328.

Du, J. Z.; Chen, Y. M. "Organic-inorganic hybrid nanoparticles with a complex hollow structure", Angew. Chem.-Int. Edit. 2004, 43(38), 5084-5087.

Deng, G. H.; Cao, M.; Huang, J.; He, L. H.; Chen, Y. M. "One-pot synthesis of star polymer by ATRP of bismaleimide and an excess of styrene with a conventional initiator", Polymer 2005, 46(15), 5698-5701.

He, L. H.; Huang, J.; Chen, Y. M.; Liu, L. P. "Inclusion complexation between comblike PEO grafted polymers and alpha-cyclodextrin", Macromolecules 2005, 38(8), 3351-3355.

He, L. H.; Huang, J.; Chen, Y. M.; Xu, X. J.; Liu, L. P. "Inclusion interaction of highly densely PEO grafted polymer brush and alpha-cyclodextrin", Macromolecules 2005, 38(9), 3845-3851.

Zhang, Y. H.; Huang, J.; Chen, Y. M. "Reactive dendronized copolymer of styryl dendron and maleic anhydride: A single molecular scaffold", Macromolecules 2005, 38(12), 5069-5077.

Chen, Y. M.; Du, J. Z.; Xiong, M.; Zhang, K.; Zhu, H. "Gelation inside block copolymer aggregates and organic/inorganic nanohybrids", Macromolecular Rapid Communications 2006, 27(10), 741-750. [Feature article]

Liu, Q. C.; Chen, Y. M. "Synthesis of well-defined macromonomers by the combination of atom transfer radical polymerization and a click reaction", Journal of Polymer Science Part A-Polymer Chemistry 2006, 44(20), 6103-6113.

Zhang, L. W.; Chen, Y. M. "Allyl functionalized telechelic linear polymer and star polymer via RAFT polymerization", Polymer 2006, 47(15), 5259-5266.

Zhang, Y.; Li, X. K.; Deng, G. H.; Chen, Y. M. "Novel hybrid polymer brushes with alternating dendritic wedges and linear side chains", Macromolecular Chemistry and Physics 2006, 207(15), 1394-1403.

Chen, Y. M.; Du, J. Z.; Xiong, M.; Guo, H. X.; Jinnai, H.; Kaneko, T. "Perforated block copolymer vesicles with a highly folded membrane", Macromolecules 2007, 40(13), 4389-4392.

Wang, Z. M.; Chen, Y. M. "Supramolecular hydrogels hybridized with single-walled carbon nanotubes", Macromolecules 2007, 40(9), 3402-3407.

Xiong, X. Q.; Chen, Y. M.; Feng, S.; Wang, W. "Codendronized polymers: Wormlike molecular objects with a segmented structure", Macromolecules 2007, 40(25), 9084-9093.

Zhang, K.; Gao, L.; Chen, Y. M. "Organic-inorganic hybrid materials by self-gelation of block copolymer assembly and nanoobjects with controlled shapes thereof", Macromolecules 2007, 40(16), 5916-5922.

Zhu, H.; Liu, Q. C.; Chen, Y. M. "Reactive block copolymer vesicles with an epoxy wall", Langmuir 2007, 23(2), 790-794.

Jiao, Q.; Yi, Z.; Chen, Y. M.; Xi, F. "Dendronized polymer as building block for layer-by-layer assembly: Polyelectrolyte multilayer films for incorporation and controlled release of water-insoluble dye", Polymer 2008, 49(6), 1520-1526.

Ren, L. X.; Ke, F. Y.; Chen, Y. M.; Liang, D. H.; Huang, J. "Supramolecular ABA triblock copolymer with polyrotaxane as B block and its hierarchical self-assembly", Macromolecules 2008, 41(14), 5295-5300.

Xiong, M.; Chen, Y. M.; Maskos, M. "Functionalization of crosslinked vesicles by co-self-assembly of a gelable diblock copolymer and mercaptosilane", Macromolecular Rapid Communications 2008, 29(16), 1368-1371.

Yi, Z.; Zhang, Y. H.; Chen, Y. M.; Xi, F. "Synthesis of novel rod-coil Amphiphilic block copolymers PAA-b-DPS with Frechet-type dendronized polystyrene and poly(acrylic acid)", Macromolecular Rapid Communications 2008, 29(9), 757-762.

Zhang, K.; Gao, L.; Chen, Y. M. "Smart organic/inorganic hybrid nanoobjects with controlled shapes by self-assembly of gelable block copolymers", Macromolecules 2008, 41(5), 1800-1807.

Zhang, K.; Gao, L.; Chen, Y. M.; Yang, Z. Z. "Onionlike spherical polymer composites with controlled dispersion of gold nanoclusters", Chemistry of Materials 2008, 20(1), 23-25.

Zhang, K.; Yu, X. L.; Gao, L.; Chen, Y. M.; Yang, Z. Z. "Mesostructured spheres of organic/inorganic hybrid from gelable block copolymers and arched nano-objects thereof", Langmuir 2008, 24(13), 6542-6548.

Zhu, H.; Deng, G. H.; Chen, Y. M. "Amphiphilic polymer brushes with alternating PCL and PEO grafts through radical copolymerization of styrenic and maleimidic macromonomers", Polymer 2008, 49(2), 405-411.

Feng, S.; Xiong, X. Q.; Zhang, G. L.; Xia, N.; Chen, Y. M.; Wang, W. "Hierarchical Structure in Oriented Fibers of a Dendronized Polymer", Macromolecules 2009, 42(1), 281-287.

Chen, Y. M.; Xiong, X. Q. "Tailoring dendronized polymers", Chemical Communications 2010, 46(28), 5049-5060. [Feature article]

Deng, G. H.; Tang, C. M.; Li, F. Y.; Jiang, H. F.; Chen, Y. M. "Covalent Cross-Linked Polymer Gels with Reversible Sol-Gel Transition and Self-Healing Properties", Macromolecules 2010, 43(3), 1191-1194.

Jiang, X. B.; Chen, Y. M.; Xi, F. "Stepwise Cleavable Star Polymers and Polymeric Gels Thereof", Macromolecules 2010, 43(17), 7056-7061.

Qin, J. L.; Chen, Y. M.; Yan, D. D.; Xi, F. "Dispersible Shaped Nanoobjects from Bulk Microphase Separation of High T-g Block Copolymers without Chemical Cross-linking", Macromolecules 2010, 43(24), 10652-10658.

Qin, J. L.; Jiang, X. B.; Gao, L.; Chen, Y. M.; Xi, F. "Functional Polymeric Nanoobjects by Cross-Linking Bulk Self-Assemblies of Poly(tert-butyl acrylate)-block-poly(glycidyl methacrylate)", Macromolecules 2010, 43(19), 8094-8100.

Tsai, C. C.; Leng, S. W.; Jeong, K. U.; Van Horn, R. M.; Wang, C. L.; Zhang, W. B.; Graham, M. J.; Huang, J.; Ho, R. M.; Chen, Y. M.; Lotz, B.; Cheng, S. Z. D. "Supramolecular Structure of beta-Cyclodextrin and Poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) Inclusion Complexes", Macromolecules 2010, 43(22), 9454-9461.

Zhang, K.; Gao, L.; Chen, Y. M. "Organic/inorganic nanoobjects with controlled shapes from gelable triblock copolymers", Polymer 2010, 51(13), 2809-2817.

Zhang, W. L.; Li, Y. L.; Liu, L. X.; Sun, Q. Q.; Shuai, X. T.; Zhu, W.; Chen, Y. M. "Amphiphilic Toothbrushlike Copolymers Based on Poly(ethylene glycol) and Poly(epsilon-caprolactone) as Drug Carriers with Enhanced Properties", Biomacromolecules 2010, 11(5), 1331-1338.

Zhu, W.; Li, Y. L.; Liu, L. X.; Chen, Y. M.; Wang, C.; Xi, F. "Supramolecular Hydrogels from Cisplatin-Loaded Block Copolymer Nanoparticles and alpha-Cyclodextrins with a Stepwise Delivery Property", Biomacromolecules 2010, 11(11), 3086-3092.

Gao, L.; Zhang, K.; Chen, Y. M. "Functionalization of shaped polymeric nanoobjects via bulk co-self-assembling gelable block copolymers with silane coupling agents", Polymer 2011, 52(17), 3681-3686.

Qin, J. L.; Chen, Y. M. "Shaped core-shell nanoparticles prepared from self-assembly of block copolymers ", Acta Polymerica Sinica 2011, (6), 572-585.

Chen, Y. M. "Shaped Hairy Polymer Nanoobjects", Macromolecules 2012, 45(6), 2619-2631.[Perspective]

Cui, Y.; Yao, D. D.; Chen, Y. M.; Wang, Z. H. "Synthesis and properties of novel functional polymers from tetrachlorinated perylene bisimide", Journal of Polymer Science Part A-Polymer Chemistry 2012, 50(17), 3485-3492.

Deng, G. H.; Li, F. Y.; Yu, H. X.; Liu, F. Y.; Liu, C. Y.; Sun, W. X.; Jiang, H. F.; Chen, Y. M. "Dynamic Hydrogels with an Environmental Adaptive Self-Healing Ability and Dual Responsive Sol-Gel Transitions", ACS Macro Letters 2012, 1(2), 275-279.

Gao, L.; Zhang, K.; Chen, Y. M. "Dumpling-Like Nanocomplexes of Foldable Janus Polymer Sheets and Spheres", ACS Macro Letters 2012, 1(9), 1143-1145.

Liu, F. Y.; Li, F. Y.; Deng, G. H.; Chen, Y. M.; Zhang, B. Q.; Zhang, J.; Liu, C. Y. "Rheological Images of Dynamic Covalent Polymer Networks and Mechanisms behind Mechanical and Self-Healing Properties", Macromolecules 2012, 45(3), 1636-1645.

Peng, B.; Liu, Y.; Shi, Y.; Li, Z. B.; Chen, Y. M. "Thermo-responsive organic-inorganic hybrid vesicles with tunable membrane permeability", Soft Matter 2012, 8(48), 12002-12008.

Wang, F.; Shi, Y.; Luo, S. J.; Chen, Y. M.; Zhao, J. "Conformational Transition of Poly(N-isopropylacrylamide) Single Chains in Its Cononsolvency Process: A Study by Fluorescence Correlation Spectroscopy and Scaling Analysis", Macromolecules 2012, 45(22), 9196-9204.

Zhao, P.; Liu, L. X.; Feng, X. Q.; Wang, C.; Shuai, X. T.; Chen, Y. M. "Molecular Nanoworm with PCL Core and PEO Shell as a Non-spherical Carrier for Drug Delivery", Macromolecular Rapid Communications 2012, 33(16), 1351-1355.

Zhao, P.; Yan, Y. C.; Feng, X. Q.; Liu, L. X.; Wang, C.; Chen, Y. M. "Highly efficient synthesis of polymer brushes with PEO and PCL as side chains via click chemistry", Polymer 2012, 53(10), 1992-2000.

Zou, L.; Zhu, W.; Chen, Y. M.; Xi, F. "Modification of side chain terminals of PEGylated molecular bottle brushes-A toolbar of molecular nanoobjects", Polymer 2013, 54(2), 481-484.

Zhu, W.; Zhang, K.; Chen, Y. M.; Xi, F. “Simple, Clean Preparation Method for Cross-Linked α-Cyclodextrin Nanoparticles via Inclusion Complexation”, Langmuir 2013, 29(20), 5939-5943.

Shi, Y.; Zhu, W.; Chen, Y. M. “Synthesis of Cylindrical Polymer Brushes with Umbrella-Like Side Chains via a Combination of Grafting-from and Grafting-onto Methods”, Macromolecules 2013, 46(6), 2391-2398.

Yao, D. D.; Guo, Y. J.; Chen, S. G.; Tang, J. N.; Chen, Y. M. "Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation", Polymer 2013, 54, 3485-3491.

Yan, Y. C.; Shi, Y.; Zhu, W.; Chen, Y. M. "Highly efficient synthesis of cylindrical polymer brushes with various side chains via click grafting-onto approach", Polymer 2013, 54, 5634-5642.

Peng, B.; Chu, X.; Li, Y. Y.; Li, D. S.; Chen, Y. M.; Zhao, J. "Adsorption kinetics and stability of poly(ethylene oxide)-block-polystyrene micelles on polystyrene surface", Polymer 2013, 54, 5779-55780.

Wang, J.; Zhu, W.; Peng, B.; Chen, Y. M. "A facile way to prepare crystalline platelets of block copolymers by crystallization-driven self-assembly", Polymer 2013, 54, 6760-6767.

Li Y. Y.; Peng B.; Chen Y. M. "Encapsulation properties of reverse-amphiphilic core/shell polymeric nanoobjects with different shapes", Journal of Materials Chemistry B 2013, 1(41), 5694-5701.

Jiang X. B.; Hu L.; Chen Y. M. "Synthesis and properties of amphiphilic star block copolymers with star macroinitiators based on a one‐pot approach", Polymer International 2013, 62(12), 1777-1782.

Peng B.; Li Y. Y.;, Zhao Z. G.; Chen Y. M.; Han C. C. "Facile surface modification of PVDF microfiltration membrane by strong physical adsorption of amphiphilic copolymers", Journal of Applied Polymer Science 2013, 130(5), 3112-3121.

Zou L.; Liu J. A.; Zhang K.; Chen Y. M."Cyclopolymerization of α, ω‐heterodifunctional monomers containing styrene and maleimide moieties", Journal of Polymer Science Part A: Polymer Chemistry 2014, 52(3), 330-338.

Wang S. S.; Zhang K.; Chen Y. M.; Xi F. "Isomeric Dicyclic Polymers via Atom Transfer Radical Polymerization and Atom Transfer Radical Coupling Cyclization", Macromolecules 2014, 47(6), 1993-1998.

Wang S. S.; Yang X. K.; Zhu W.; Zou L.; Zhang K.; Chen Y. M.; Xi F. "Strain-promoted azide-alkyne cycloaddition “click” as a conjugation tool for building topological polymers", Polymer 2014, 55(19), 4812-4819.

Zhu W.; Zhang K.; Chen Y. M. "Block copolymer micelles as carriers of transition metal ions Y (III) and Cu (II) and gelation thereof", Polymer 2014, 55(24), 6232-6238.

Zou L.; Long M. L.;, Zhou H. B.; Zhu W.; Zhang K.; Chen Y. M.; Xi F. "C (sp 3)–C (sp 3) coupling polymerization of alkyl dibromides for preparation of polymers with precisely located phenyl pendants", Polymer 2015, 64, 196-201.

Yang G. L.; Zhang R.; Huang H. H.; Liu L. X.; Wang L.; Chen Y. M. "Synthesis of novel biobased polyimides derived from isomannide with good optical transparency, solubility and thermal stability", RSC Advances 2015, 5(83), 67574-67582.

Ruan Y. B.; Gao L.; Yao D. D.; Zhang K.; Zhang B. Q.; Chen Y. M.; Liu C. Y. "Polymer-grafted nanoparticles with precisely controlled structures", ACS Macro Letters 2015, 4(10), 1067-1071.

Sun P.; Yan G. W.; Tang Q. Q.; Chen Y. M.; Zhang K. "Well-defined cyclopropenone-masked dibenzocyclooctyne functionalized polymers from atom transfer radical polymerization", Polymer 2015, 64, 202-209.

Yao D. D.; Chen Y. M.; Jin R. H. "Different dimensional silica materials prepared using shaped block copolymer nanoobjects as catalytic templates", Journal of Materials Chemistry B 2015, 3(28), 5786-5794.

Yang C.; Wu B.; Chen Y. M.; Zhang K. "Gels based on anion recognition between triurea receptor and phosphate anion", Macromolecular rapid communications 2015, 36(8), 750-754.

Long M. L.; Shi Y.; Zhang K.; Chen Y. M. "Microphase Separation within Disk Shaped Aggregates of Triblock Bottlebrushes", Macromolecular rapid communications 2016, 37, 605-609.

Yao D. D.; Zhang K.; Chen Y. M. "Microphase separation of poly (tert-butyl methacrylate)-block-polystyrene diblock copolymers to form perforated lamellae", Polymer 2016, 94, 1-7.

Xiao L. F.; Chen Y. M.; Zhang K. "Efficient Metal-Free “Grafting Onto” Method for Bottlebrush Polymers by Combining RAFT and Triazolinedione–Diene Click Reaction", Macromolecules 2016, 49(12), 4452-4461.

Zhu W.; Zhang L. C.; Chen Y. M.; Zhang K. "A UV‐Cleavable Bottlebrush Polymer with o‐Nitrobenzyl‐Linked Side Chains", Macromolecular Rapid Communications 2017.

Zhou H. B.; Chen Y.; Plummer C. M.; Huang H. H.; Chen Y. M. "Facile and efficient bromination of hydroxyl-containing polymers to synthesize well-defined brominated polymers", Polymer Chemistry 2017, 8, 2189-2196.

He Z. Y.; Santos J. L.; Tian H. K.; Huang H. H.; Hu Y. Z.; Liu L. X.; Leong K. W.; Chen Y. M.; Mao H. Q. "Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin", Biomaterials 2017, 130, 28-41.

Zhou H. B.; Wang S. S.; Huang H. H.; Li Z. Y.; Plummer C. M.; Wang S. L.; Sun W. H.; Chen Y. M. "Direct Amination of Polyethylene by Metal-Free Reaction", Macromolecules 2017, 50, 3510-3515.

Li T. Y.; Huang H. H.; Wang L.; Chen Y. M. "High performance polyimides with good solubility and optical transparency formed by the introduction of alkyl and naphthalene groups into diamine monomers", RSC Advances 2017, 7, 40996-41003.

Sun Z. Y.; Huang H. H.; Li L.; Liu L. X.; Chen Y. M. "Polythioamides of High Refractive Index by Direct Polymerization of Aliphatic Primary Diamines in the Presence of Elemental Sulfur", Macromolecules 2017, 50, 8505-8511.

Chu Y. H.; Li H. A.; Huang H. H.; Zhou H. B.; Chen Y.; Andreas B.; Liu L. X.; Chen Y. M. "Uni-molecular nanoparticles of poly(2-oxazoline) showing tunable thermoresponsive behaviors", Journal of Polymer Science Part A: Polymer Chemistry 2018, 56, 174-183.

Plummer C. M.; Zhou H. B.; Zhu W.; Huang H. H.; Liu L. X.; Chen Y. M. "Mild halogenation of polyolefins using an N-haloamide reagent", Polymer Chemistry 2018, 9, 1309-1317. 

Hu Z. T.; Chen Y.; Huang H. H.; Liu L. X.; Chen Y. M. "Well-Defined Poly(α-amino-δ-valerolactone) via Living Ring-Opening Polymerization", Macromolecules 2018, 51, 2526-2532.

Wu X. L.; Wu Y. D.; Wang Z. Y.; Liu L. X.; Sun C. X.; Chen Y. M.; Wang C. "A Cascade‐Targeting Nanocapsule for Enhanced Photothermal Tumor Therapy with Aid of Autophagy Inhibition", Advanced Healthcare Materials 2018.

He Z. Y.; Liu Z. J.; Tian H. H.; Hu Y. Z.; Liu L. X.; Leong K. W.; Mao H. Q.; Chen Y. M. "Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin", Nanoscale 2018, 10, 3307-3319.

Qiao D. D.; Liu L. X.; Chen Y.; Xue C. B.; Gao Q.; Mao H. Q.; Leong K. W.; Chen Y. M. "Potency of a Scalable Nanoparticulate Subunit Vaccine", Nano Letters 2018, 18, 3007-3016.

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