刘志佳

个人基本简介: 

职称:副教授

学位:博士

毕业学校:复旦大学

电子邮件:liuzhj9@mail.sysu.edu.cn

通讯地址:广州市海珠区新港西路135号丰盛堂C座,邮编510275

 

主要经历: 

2019年-,中山大学材料科学与工程学院,副教授,硕士生导师

2016-2019年,中山大学材料科学与工程学院,特聘副研究员

2011-2016年,复旦大学高分子科学系,理学博士

2007-2011年,湘潭大学化学学院,工学学士

学科方向: 

高分子合成与转化医学;药物传输与缓释载体;口服药物递送;生物医用水凝胶;炎症与免疫治疗

荣誉获奖: 

2016年,复旦大学首届“龙盛-于同隐”卓越学生奖

主要兼职: 

1. 主持国家自然科学基金项目,中山大学青年教师培育项目等

2. 担任ACS Appl. Mater. Interfaces, ACS Macro Lett., Nanoscale, Carbohyd. Polym., Clin. Pharmacokinet., Int. J. Pharm.等国际权威期刊审稿人

代表论著: 

发表论文:

  1. Yan Xu, Youzhi Wang, Quanli Yang, Zhijia Liu, Zhiqiang Xiao, Zhicheng Le, Zhimou Yang*, Chengbiao Yang*. A versatile supramolecular nanoadjuvant that activates NF-κB for cancer immunotherapy. Theranostics 2019, 9, 3388-3397.

  2. Zhijia Liu*, Zhicheng Le, Liejing Lu, Ying Zhu, Chengbiao Yang, Pengfei Zhao, Zhiyong Wang, Jun Shen, Lixin Liu, Yongming Chen*. Scalable production of metal-phenolic nanoparticles by coordination-driven flash nanocomplexation for cancer theranostics. Nanoscale 2019, 11, 9410-9421.

  3. Zhiyu He, Yizong Hu, Zaizhi Gui, Yang Zhou, Tianqi Nie, Jinchang Zhu, Zhijia Liu, Kuntao Chen, Lixin Liu, Kam W Leong, Peng Cao*, Yongming Chen*, Hai-Quan Mao*. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. J. Controlled Release 2019, 301, 119-128.

  4. Zhicheng Le, Zhijia Liu*, Yongming Chen. Progress of polymeric nanocarriers-mediated oral delivery of chemotherapeutics. Polym. Mater. Sci. Eng. 2019, accepted.

  5. Lilong Sun, Zhijia Liu*, Houkuan Tian, Zhicheng Le, Lixin Liu, Kam W. Leong, Hai-Quan Mao, Yongming Chen*. Scalable manufacturing of enteric encapsulation systems for site-specific oral insulin delivery. Biomacromolecules 2019, 20, 528-538.

  6. Zhipeng Zeng, Cong Dong, Pengfei Zhao, Zhijia Liu, Lixin Liu*, Hai-Quan Mao, Kam W. Leong, Xiaohu Gao*, Yongming Chen*. Scalable production of therapeutic protein nanoparticles using flash nanoprecipitation. Adv. Healthcare Mater. 2019, 8, 1801010.

  7. Zhicheng Le, Yantao Chen, Honghua Han, Houkuan Tian, Pengfei Zhao, Chengbiao Yang, Zhiyu He, Lixin Liu, Kam W. Leong, Hai-Quan Mao, Zhijia Liu*, Yongming Chen*. Hydrogen-bonded tannic acid-based anticancer nanoparticle for enhancement of oral chemotherapy. ACS Appl. Mater. Interfaces 2018, 10, 42186-42197.

  8. Houkuan Tian, Zhiyu He, Chengxin Sun, Chengbiao Yang, Pengfei Zhao, Lixin Liu, Kam W. Leong, Hai-Quan Mao*, Zhijia Liu*, Yongming Chen*. Uniform core-shell nanoparticles with thiolated hyaluronic acid coating to enhance oral delivery of insulin. Adv. Healthcare Mater. 2018, 7, 1800285.

  9. Zhiyu He, Zhijia Liu, Houkuan Tian, Yizong Hu, Lixin Liu, Kam W. Leong*, Hai-Quan Mao*, Yongming Chen*. Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. Nanoscale 2018, 10, 3307-3319.

  10. Zhijia Liu, Guangrui Xu, Chaonan Wang, Chunyang Li, Ping Yao*. Shear-responsive injectable supramolecular hydrogel releasing doxorubicin loaded micelles with pH-sensitivity for local tumor chemotherapy. Int. J. Pharm. 2017, 530, 53-62.

  11. Baoru Yin, Chaonan Wang, Zhijia Liu, Ping Yao*. Peptide-polysaccharide conjugates with adjustable hydrophilicity/hydrophobicity as green and pH sensitive emulsifiers. Food Hydrocolloids 2017, 63, 120-129.

  12. Chunyang Li, Zhijia Liu, Ping Yao*. Gold nanoparticles coated with a polydopamine layer and dextran brush surface for diagnosis and highly efficient photothermal therapy of tumors. RSC Adv. 2016, 6, 33083-33091.

  13. Chaonan Wang, Zhijia Liu, Guangrui Xu, Baoru Yin, Ping Yao*. BSA-dextran emulsion for protection and oral delivery of curcumin. Food hydrocolloids 2016, 61, 11-19.

  14. Zhe Zhang, Huanxin Cai, Zhijia Liu, Ping Yao*. Effective enhancement of hypoglycemic effect of insulin by liver-targeted nanoparticles containing cholic acid-modified chitosan derivative. Mol. Pharmaceutics 2016, 13, 2433-2422.

  15. Zhijia Liu, Ping Yao*. Injectable shear-thinning xanthan gum hydrogel reinforced by mussel-inspired secondary crosslinking. RSC Adv. 2015, 5, 103292-103301.

  16. Zhijia Liu, Ping Yao*. Injectable thermo-responsive hydrogel composed of xanthan gum and methylcellulose double networks with shear-thinning property. Carbohyd. Polym. 2015, 132, 490-498.

  17. Zhijia Liu, Ping Yao*. Versatile injectable supramolecular hydrogels containing drug loaded micelles for delivery of various drugs. Polym. Chem. 2014, 5, 1072-1081.

发明专利:

  1. 刘志佳,田厚宽,陈永明,刘利新,梁锦荣,毛海泉;一种口服艾塞那肽纳米颗粒制剂及其制备方法和应用,发明专利号:201811063975.3.

  2. 刘志佳,田厚宽,陈永明,刘利新,孙立泷,乐志成;一种基于氢键络合的多肽或蛋白纳米制剂及其制备方法和应用,发明专利号:201811063976.8.

  3. 刘志佳,孙立泷,陈永明,毛海泉,梁锦荣,刘利新,孙成新;一种负载胰岛素的肠溶性纳微颗粒及其制备方法和应用,发明专利号:201810108109.5, PCT/CN2018/101177.

  4. 刘志佳,田厚宽,陈永明,毛海泉,梁锦荣,刘利新,何治宇,孙成新;一种口服胰岛素纳米颗粒制剂及其制备方法和应用,发明专利号:201810107604.4, PCT/CN2018/101176.

  5. 刘志佳,乐志成,陈永明, 刘利新,梁锦荣,毛海泉;一种基于单宁酸的载药纳米颗粒及其制备方法和应用,发明专利号:201810027997.8, PCT/CN2018/101178.

  6. 孙成新,刘利新,陈永明,何治宇,刘志佳;罗布麻酸性多糖穿膜肽口服胰岛素纳米复合物的制备方法,发明专利号:201710093564.8.

  7. 姚萍,刘志佳;可注射型载药黄原胶/甲基纤维素复合溶液及制备方法,发明专利号:201410289958.7.

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